Fludrocortisone in Septic Shock
The Surviving Sepsis 2021 Campaign makes a weak recommendation for the addition of steroids in patients with ongoing pressor requirements. They provide a recommendation for IV hydrocortisone 200 mg per day based on the ADRENAL, VANISH, and the APROCCHSS trials. The APROCCHSS trial showed a mortality benefit when hydrocortisone and fludrocortisone were added in septic shock versus placebo. The role of fludrocortisone was not addressed in the 2021 Surviving Sepsis Campaign; however, newer trials have hinted at potential benefit when added to hydrocortisone. The goal of this pharmacotherapy rounds is to assess the possible utility of fludrocortisone in septic shock.
This activity is a recording from a live webinar (on 12/17/2024) and those that claim credit for the live webinar should not claim credit for this activity.
CE Credit: 0.5 Contact Hours
Universal Activity Number (UAN): 0025-0000-24-104-H01-P
Activity Type: Application
Launch Date: 12/17/2024
Expiration Date: 12/17/2025
Course Number: HTIP_2024_12_17_Smith
Target Audience: Pharmacists
Course Details (Activity Announcement): View File (HTIP_2024_12_17_Smith Activity Announcement)
Presenter:
Natalia Smith, PharmD
PGY-2 Critical Care Pharmacy Resident
University of Maryland
Dr. Smith, faculty for this activity, has no financial relationship(s) to disclose. None of the planners for this activity have financial relationships to disclose.
The University of Maryland School of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
Learning Objectives
At the end of this activity, the participant should be able to:
- Describe key recommendations regarding corticosteroid use from the surviving sepsis 2021 campaign.
- Evaluate the data regarding fludrocortisone use in septic shock.
- Formulate a corticosteroid treatment plan for septic shock.
Instructor
Natalia Smith, PharmD
PGY-2 Critical Care Pharmacy Resident
University of Maryland
Dr. Smith, faculty for this activity, has no financial relationship(s) to disclose. None of the planners for this activity have financial relationships to disclose.
Technology Requirements
Unless otherwise noted in the course materials, the following are required to access online courses: A computer or mobile device with a stable internet connection and the ability to view and update Microsoft Word® and PowerPoint® documents.
| Supported Internet Browsers |
Windows
- Internet Explorer version 11 and above
- Chrome 43 and above
- Firefox 4.0 (or later)
MacOS
- Safari 13 and above
- Chrome 43 and above
|
| Minimum Memory |
8 GB (or more) |
| Minimum Storage |
6 GB (or more) |
| Minimum Processor |
PC: 2 GHz or faster Intel processor
MacOS: Multi-core Intel processor |
| Minimum Internet Speeds |
High speed internet connection |
| Other |
Participants must be able to play audio (either through speakers or headphones) as well as ability to open PDF files and view and edit Word, and PPT documents. |
Successful completion requires the participant to complete all activity components including the audiovisual presentations, active leanring, and activity evaluation. Learners must complete the activity evaluation in order to receive CE credit. A link to the activity evaluation will be available once a learner has successfully completed all other course segments.
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